Search results for " Forensic genetics"

showing 2 items of 2 documents

The molecular characterization of a depurinated trial DNA sample can be a model to understand the reliability of the results in forensic genetics

2014

The role of DNA damage in PCR processivity/fidelity is a relevant topic in molecular investigation of aged/forensic samples. In order to reproduce one of the most common lesions occurring in postmortem tissues, a new protocol based on aqueous hydrolysis of the DNA was developed in vitro. Twenty-five forensic laboratories were then provided with 3.0 μg of a trial sample (TS) exhibiting, in mean, the loss of 1 base of 20, and a molecular weight below 300 bp. Each participating laboratory could freely choose any combination of methods, leading to the quantification and to the definition of the STR profile of the TS, through the documentation of each step of the analytical approaches selected. …

DNA depurination; Forensic genetics; PCR fidelity; STR typing; Biochemistry; Clinical BiochemistryPCR fidelityGenotyping TechniquesDNA damageSample (material)Clinical BiochemistryDNA depurinationReproducibility of ResultForensic geneticsBiologyPolymerase Chain ReactionBiochemistryNOAnalytical Chemistrylaw.inventionDNA depurination; PCR fidelity; STR typing; forensic genetics.Settore MED/43 - Medicina LegalelawSettore BIO/13 - Biologia ApplicataGenotypeHumansSTR typingGenotyping TechniquesPolymerase chain reactionProtocol (science)GeneticsMedicine (all)Reproducibility of ResultsForensic geneticDNAAmpliconDNA FingerprintingDNA depurination; Forensic genetics; PCR fidelity; STR typingSettore BIO/18 - GeneticaDNA depurination Forensic genetics PCR fidelity STR typingDNA profilingSettore MED/03 - Genetica MedicaMicrosatellite RepeatGenotyping TechniqueDNA depurination; Forensic genetics; PCR fidelity; STR typing;Microsatellite RepeatsHuman
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PROVA TECNICA E CONTRADDITTORIO NEL PROCESSO PENALE

2023

When science and the criminal process come into contact, cognitive mechanisms are set in motion aimed at reorganizing knowledge belonging to worlds other than the legal one. In this context, the actors of the trial scene are forced to move on a hybrid terrain in which judicial epistemology and scientific epistemology mix. Such a fascinating picture pushes the scholar of the criminal process to seek interpretations suitable for explaining the multiple dilemmas that the phenomenon entails. Starting from a historical-legislative excursus of the expert evidence, the proposed analysis examines the different channels through which expert knowledge enters the process, starting from the investigati…

Expert witness right to confrontation cross examination scientific epistemology judicial epistemology digital forensics forensic genetics investigations best practices freedoms and fundamental rights of the person BARD system of the controls of the decisionSettore IUS/16 - Diritto Processuale Penale
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